I've been using ActiveState's Komodo for a few weeks now in response to my frustrations with Eclipse. As with any IDE there was a short relearning of my ways that was necessary, but I am happy to report that I really like this IDE. The last bit of functionality I've been wanting to tie together is directly related to debugging Drupal in Komodo. Here's the steps that I took to get a Drupal development environment with debugging in Komodo on a clean installation of a 64bit Ubuntu 8.04.
A good deal of this may be redundant if you already have your environment established, but it is recorded here nonetheless to help others become proficient at what we do. While I prefer command line interfaces I am going to lean towards providing gui tools to allow newer devs options. If you don't need or want all of the minute details skip to step 6 and get straight into configuring for debugging.